Drugs Used in Peptic Ulcer

Various drugs are used to treat. gastric ulcers. The selection of the drug used in the treatment of ulcers depends on by various patient-specific factors, as well as the underlying cause of the ulcer.

Peptic ulcer disease is most often caused by an infection with the gram-negative bacteria Helicobacter pylori or by taking nonsteroidal anti-inflammatory drugs (NSAIDs). Increased production of hydrochloric acid. (HCl) and a lack of protection. of the membrane from stomach acid also play a part. Following are the approaches to manage peptic ulcer

1) Getting rid of the H. pylori infection

2) Lowering the amount of stomach acid with PPIs or H2 receptor blockers.

3) Protecting the gastric mucosa from damage

Classification of Drugs

Proton Pump Inhibitors (PPIs)

PPIs are an essential component of peptic ulcer therapy. They reduce the formation of stomach acid and promote in ulcer repair.

Omeprazole

Esomeprazole

Lansoprazole

Pantoprazole

Rabeprazole

Histamine-2 Receptor Antagonists (H2 Blockers)

H2 blockers reduce. gastric acid production by blocking histamine-2 receptors on parietal cells in the stomach.

Ranitidine

Famotidine

Cimetidine

Nizatidine

Antacids

By neutralising stomach acid, antacids can give symptomatic relief. They are frequently used as a supplement to therapy for short-term symptom mitigation.

Antacids provide short-term relief by neutralizing stomach acid. They work by raising the pH of the stomach contents, reducing the acidity.

Non-systemic

Aluminum Hydroxide

Magnesium Hydroxide

Calcium Carbonate

Magnesium Trisilicate

Systemic

Sodium Bicarbonate

Sodium Citrate

Antibiotics

When a peptic ulcer is attributed to an infection. caused by Helicobacter pylori (H. pylori), the recommended course of action involves prescribing a combination of antibiotics to effectively eliminate the bacteria.

Amoxicillin

Clarithromycin

Metronidazole

Tetracycline

Minocycline